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Book Details:

• Author: Johnny Stiban
• Date: 20 Sep 2019
• Publisher: Springer Nature Switzerland AG
• Original Languages: English
• Book Format: Hardback::153 pages
• ISBN10: 3030211614
• ISBN13: 9783030211615
• File size: 33 Mb
• Dimension: 178x 254x 14mm::679g
• Download: Bioactive Ceramides in Health and Disease : Intertwined Roles of Enigmatic Lipids

Bioactive Ceramides in Health and Disease: Intertwined Roles of Enigmatic Lipids Johnny Stiban English | PDF,EPUB | 2019 | 159 Pages | ISBN:3030211614 | 17.72 MB This book is about the various roles of bioactive ceramides and other sphingolipids in cellular biology. The enigmatic biophysical and biochemical properties of ceramides and their propensity to influence This highlights the complexity of the system in health and disease, and the need for a controlled production of both cytokines. We describe here only one mechanism of how IL-17A/IL-22 induce a context-specific epithelial cell response that potentially impacts on the order or composition of immune cell infiltration. Heat Shock Protein 90 in Human Diseases and Disorders Heat Shock Bioactive Ceramides in Health and Disease Intertwined Roles of Enigmatic Lipids. Retrouvez Bioactive Ceramides in Health and Disease: Intertwined Roles of Enigmatic Lipids et des millions de livres en stock sur Achetez neuf ou Lipids from homogenates of embryos at E11.5 were extracted adding 1 ml of 25 mM HCl-1 M NaCl, 1 ml of methanol, 1 ml of chloroform, and 100 μl of 3 N NaOH. After phase separation, the aqueous phase containing S1P was transferred to a siliconized glass tube and the organic phases were re-extracted with 1 ml of methanol-1 M NaCl (1:1, vol/vol). Chronic diseases, which include cardiovascular disease, diabetes, obesity, and cancer, kill more than 36 million people each year. These diseases have been linked to an individual s behavior and/or genetic health history. Some college students engage in risky behaviors, such as smoking, drinking, physical inactivity, unhealthy eating, and stress. Ceramide is an important lipid signaling molecule that plays critical roles in regulating cell behavior. Ceramide synthesis is surprisingly complex and is orchestrated six mammalian ceramide 1. Introduction. Thudichum (84) referred to sphingolipids (from the Greek sphinx) as a peculiar group of lipids because of their enigmatic nature [].Ceramides represent the structural backbone common to all sphingolipids [].Moreover, they regulate several key cellular processes, including cell cycle, cell growth and differentiation, as well as cell death. Bioactive Ceramides in Health and Disease [electronic resource]:Intertwined Roles of Enigmatic Lipids [2019]. Cham:Springer, 2019. Description: Book 1 Analyzing gene expression from whole tissue vs. Different cell types reveals the central role of neurons in predicting severity of Alzheimer's disease. September 28, 2012 [ MEDLINE Abstract ] gether, these results indicate that bioactive ceramide analogs and apoptosis. These lipids serve both a structural role in membranes and cardiovascular disease (Johns et al., 1998). Our laboratory This work was supported National Institutes of Health Grant HL66371. Intertwined roles in regulation of apoptosis. This important book develops a critical understanding of the bridging of arts and health domains, drawing on models and perspectives from social sciences to develop the case for arts and health as a social movement. Bioactive Ceramides in Health and Disease: Intertwined Roles of Enigmatic Lipids 1st ed. 2019 19-Sep-2019, Hardback proinflammatory state together with increased lipid accumulation in extra contribution of sphingolipids, including ceramide, glucosylceramide and health complications (Figure 1), and adipose disease. Emerging evidence suggest a role for sphingolipids in this process. Production of bioactive molecules including. Sep 23, 2019 Johnny Stiban, an associate professor of biology and biochemistry at Birzeit University, edited a new book on the roles of bioactive ceramides that compiles and summarizes the results of thirty years of research on sphingolipid biochemistry. The book: Bioactive Ceramides in Health and Disease: Intertwined Roles of Enigmatic Lipids was published the Food and Nutritional Supplements: Their Role in Health and Disease. Bioactive Ceramides in Health and Disease: Intertwined Roles of Enigmatic Lipids. Generation of SphK2 mutant mice. An .5-kb genomic DNA fragment of SphK2 was cloned from a 129/Sv library and characterized. As shown in Fig. Fig.1A, 1A, mouse SphK2 consists of seven exons, with the coding region located in exons 3 to 7. A plasmid construct was created replacing the region from the second half of exon 4 to the end of exon 7 with a LacZ (Source: Advances in Experimental Medicine and Biology) Adv Exp Med Biol[Journal] +111 new citations Authors: Bottoni P, Scatena R Abstract Given the role of mitochondria in modulating many cellular functions, it is not surprising that they can play a crucial role also in molecular pathophysiology of cancer. Sep 15, 2003 The two control systems are intertwined, This review updates current knowledge of sphingolipid metabolism and some of the evidence showing that ceramide plays a causal role in apoptosis induction, as well as a chemotherapeutic agent. Intermembranous movement of lipids and other cellular components is a well established process that Bioactive Ceramides in Health and Disease Intertwined Roles of Enigmatic Lipids Johnny Stiban and Publisher Springer. Save up to 80% choosing the Biology - Concordia University Libraries Recent Acquisitions. Bioactive Ceramides in Health and Disease Intertwined Roles of Enigmatic Lipids / Johnny Stiban, editor. From alcohol metabolism to human health and precision medicine / Jun Ren, Yingmei Zhang, Junbo Ge, editors. Particularly, sphinx) as a peculiar group of lipids because of their enigmatic ceramide accumulation has been implicated in the pathogenesis of mul- nature [1]. Ceramides represent the structural backbone common to tiple diseases including diabetes, cardiomyopathies and atherosclerosis all sphingolipids [2]. Nevertheless, much progress has been made, shedding light on the numerous roles these lipids play in eukaryotes. How sphingolipids are synthesized, transformed and degraded in mammalian cells, and how some of them transduce signals and regulate biological functions is The role of bioactive lipids in cancer, inflammation and related diseases Kenneth V. Honn, Darryl C. Zeldin, editors Bioactive Ceramides in Health and Disease Intertwined Roles of Enigmatic Lipids / Johnny Stiban, editor. This book explores the role of animals - horses, cattle, sheep, pigs and dogs - in shaping Georgian London. Keywords: ceramide, bioactive lipids, compartmentalization However, intensive research on SL metabolism and function has revealed Furthermore, Cer has recently been linked to Alzheimer's disease and neurodegeneration, This work was supported National Institutes of Health Grants GM-43825 and CA-87584. University of Pennsylvania ScholarlyCommons Publicly Accessible Penn Dissertations 2019 A Mendelian Disease Of Autoimmunity Reveals Gimap5 As A Novel Member Of The Buy a discounted Hardcover of Lipids and Skin Health online from Australia's Bioactive Ceramides in Health and Disease:Intertwined Roles of Enigmatic On the cover: There are a number of hypotheses as to how excess nutrients cause insulin resistance, diabetes, and fatty liver disease. For this Special Focus on Lipids and Insulin Resistance, Cell Metabolism is pleased to present ten Perspectives, each putting forward one of the leading hypotheses underlying the mechanism(s) connecting nutrients and insulin resistance. The role for PRKN and PINK1 in sphingolipid metabolism is not well established; however, their role in the cell has been linked to mitochondrial quality control and mitophagy.Mitophagy requires dynamic membrane rearrangements that depend on ceramide metabolism.What remains unclear is the role of specific ceramide species in this process. We argue that ceramides may play a critical role in the pathobiology based on the studies of PLA2G6 and VPS35 in Drosophila mutants and human knock-down cells. Sphingolipids in the Pathogenesis of Parkinson s Disease and Parkinsonism: Trends in The enigmatic biophysical and biochemical properties of ceramides and their propensity to influence membranes whether as rafts or protein-permeable channels are heavily discussed. Metabolism of ceramides and their metabolites is also focused with ceramide synthase family of proteins being a target of extensive review. The book: Bioactive Ceramides in Health and Disease: Intertwined Roles of Enigmatic Lipids was published the International Publisher Science: Springer, and written world-renowned scientists from the field of lipid biology and addresses experienced readers who are interested in reading about bioactive ceramide The emerging role of ceramide lipids in apoptosis and an increased understanding of their involvement in multidrug resistance (MDR) has revealed new opportunities for manipulating ceramide levels in order to achieve specific therapeutic objectives. Köp boken Bioactive Ceramides in Health and Disease av (ISBN Undertitel: Intertwined Roles of Enigmatic Lipids; Redaktör: Johnny Stiban; Språk: Engelska Intertwined Roles of Enigmatic Lipids Johnny Stiban a global picture of bioactive sphingolipids in health and disease is presented in a concise, yet thorough Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure,

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